{"id":194489,"date":"2021-06-06T08:18:27","date_gmt":"2021-06-06T00:18:27","guid":{"rendered":"\/\/m.catawbaoil.com\/194489.html"},"modified":"2021-06-06T08:18:27","modified_gmt":"2021-06-06T00:18:27","slug":"%e7%bf%9f%e5%b7%8d%e5%b7%8d%e7%ae%80%e5%8e%86_%e6%96%b0%e5%8a%a0%e5%9d%a1%e5%9f%ba%e5%9b%a0%e7%bb%84%e7%a0%94%e7%a9%b6%e6%89%80%e9%ab%98%e7%ba%a7%e7%a0%94%e7%a9%b6%e5%91%98%e7%bf%9f%e5%b7%8d%e5%b7%8d","status":"publish","type":"post","link":"\/\/m.catawbaoil.com\/194489.html","title":{"rendered":"\u7fdf\u5dcd\u5dcd\u7b80\u5386_\u65b0\u52a0\u5761\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\u9ad8\u7ea7\u7814\u7a76\u5458\u7fdf\u5dcd\u5dcd\u53d7\u9080\u53c2\u4f1a\u6f14\u8bb2_\u6d3b\u52a8\u5bb6"},"content":{"rendered":"

\u65b0\u52a0\u5761\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\uff0c\u9ad8\u7ea7\u7814\u7a76\u5458\uff0c\u8fdb\u5316\u57fa\u56e0\u7ec4\u5b66\u65b9\u5411\u3002\u53d1\u8868\u6587\u7ae015\u7bc7\u3002 \u5dcd\u5dcd\u535a\u58eb\u81f4\u529b\u4e8e\u7814\u7a76\u901a\u8fc7\u5168\u57fa\u56e0\u7ec4\u6570\u636e\u8fdb\u884c\u79cd\u7fa4\u6f14\u5316\u5386\u53f2\u7684\u63a8\u65ad\uff0c\u7279\u522b\u662f\u4eba\u7c7b\u548c\u5bb6\u517b\u52a8\u7269\u7684\u7fa4\u4f53\u5386\u53f2\uff1b\u540c\u65f6\uff0c\u4ed6\u7684\u7814\u7a76\u9886\u57df\u8fd8\u5305\u62ec\u80bf\u7624\u57fa\u56e0\u7ec4\u5b66\u548c\u75c5\u6bd2\u6f14\u5316\u3002 1.\u7fa4\u4f53\u9057\u4f20\u5b66(Population Genetics)\uff0c\u6211\u5bf9\u79cd\u7fa4\u9057\u4f20\u7684\u91cc\u9762\u7684\u5f88\u591a\u95ee\u9898\u90fd\u6709\u5174\u8da3\u3002\u4f8b\u5982\uff0c\u5982\u4f55\u901a\u8fc7\u5168\u57fa\u56e0\u7ec4\u6570\u636e\u67e5\u627e\u53d7\u8fc7\u81ea\u7136\u9009\u62e9\u7684\u533a\u6bb5\uff0c\u79cd\u7fa4\u7684\u6f14\u5316\u5386\u53f2\u7684\u63a8\u65ad(Demographic History Inference)\uff0c\u7279\u522b\u662f\u4eba\u7c7b\u8fc1\u79fb\u8fdb\u5316\u7684\u5386\u53f2\uff0c\u79cd\u7fa4\u95f4\/\u5185\u591a\u6001\u6027\u7684\u5206\u5e03\uff08\u4f8b\u5982\u6d89\u53ca\u4ee3\u8c22\u9176\u79cd\u5185\u591a\u6001\u6027\u7684\u836f\u7269\u57fa\u56e0\u7ec4\u5b66(Pharmacogenomics),\u4e2a\u4f53\u5316\u57fa\u56e0\u7ec4\u5b66(Personalized Genomics) \uff09\uff0c\u5e73\u8861\u9009\u62e9(Balancing Selection) \u4f5c\u7528\u4e0b\u79cd\u7fa4\u7684\u52a8\u6001\u6027\u7b49\u7b49\u3002 2.\u764c\u75c7\/\u80bf\u7624\u57fa\u56e0\u7ec4\u5b66(Cancer Genomics)\uff0c\u548c\u5434\u4ef2\u4e49\uff0c\u5415\u96ea\u6885\u4e24\u4f4d\u8001\u5e08\u4e00\u8d77\uff0c\u6211\u6709\u5e78\u63a5\u89e6\u5230\u80bf\u7624\u9057\u4f20\u5b66\u91cc\u5f88\u591a\u6709\u8da3\u7684\u95ee\u9898\u3002\u4f8b\u5982\u80bf\u7624\u7fa4\u4f53\u7684\u8fdb\u5316\u6f14\u53d8\u7684\u8fc7\u7a0b\u4e2d\uff0c\u764c\u75c7\u81f4\u75c5\u7a81\u53d8\uff08cancer causing mutation\uff09\u5728\u80bf\u7624\u7fa4\u4f53\u8fdb\u5316\u8fc7\u7a0b\u4e2d\u7684\u4f5c\u7528, \u4e2a\u4f53\u53d1\u80b2\uff08development\uff09\u548c\u8870\u8001(ageing) \u8fc7\u7a0b\u4e2d\u4f53\u7a81\u53d8\u79ef\u7d2f\u548c\u53d1\u5c55\u8fc7\u7a0b, \u764c\u75c7\u8f6c\u79fb\u7ec6\u80de\u7fa4\u548c\u539f\u53d1\u764c\u7fa4\u76f8\u4e92\u5173\u7cfb\u7b49\u7b49\u3002 3.\u5206\u5b50\u8fdb\u5316(Molecular Evolution)\uff0c\u5206\u5b50\u8fdb\u5316\u4e3b\u8981\u7814\u7a76\u7269\u79cd\u4e4b\u95f4\u5206\u5316\u7684\u8fc7\u7a0b\uff0c\u5f88\u591a\u95ee\u9898\u90fd\u5f88\u6709\u610f\u601d\u3002\u4f8b\u5982\uff1agene tree\/species tree concordance, \u7269\u79cd\u5f62\u6210\u6a21\u5f0f(Speciation mode), \u4ee5\u53ca\u5982\u4f55\u901a\u8fc7\u7269\u79cd\u95f4\u4e0d\u540c\u57fa\u56e0\u7684\u6bd4\u8f83\uff08dN\/dS\uff09\uff0c\u67e5\u627e\u90a3\u4e9b\u5728\u7269\u79cd\u95f4\u5206\u5316\u8fc7\u7a0b\u4e2d\u53d7\u8fc7\u6b63\u9009\u62e9\u7684\u57fa\u56e0\u7247\u6bb5\u7b49\u7b49\u3002 4.\u75be\u75c5\u76f8\u5173\u6027\u7814\u7a76\uff08Disease Association study\uff09, \u4f8b\u5982\u5728\u5168\u57fa\u56e0\u7ec4\u75be\u75c5\u76f8\u5173\u6027(Genome Wide Association Study) \u7814\u7a76\u4e2d\u5982\u4f55\u505aexperimental design\uff0c\u57fa\u56e0\u7ec4marker\u9009\u62e9\u4ee5\u53ca\u75be\u75c5\u57fa\u56e0\u548c\u81ea\u7136\u9009\u62e9\u4e4b\u95f4\u5173\u7cfb\u7b49\u7b49\u3002 5.\u75c5\u6bd2\u548c\u7ec6\u83cc\u7c7b\u7684\u8fdb\u5316(Viral and Microbial Evolution)\uff0c\u6211\u5bf9\u5f88\u591a\u75c5\u6bd2\u7684\u8fdb\u5316\u90fd\u6709\u5f88\u591a\u5174\u8da3\uff0c\u7279\u522b\u662f\u611f\u5192\u75c5\u6bd2\uff08Influenza virus\uff09\uff0cHBV\uff08Human Hepatitis Virus\uff09, HPV (Human Papillomavirus) \u7684\u8fdb\u5316\u6a21\u5f0f\uff0c\u81ea\u7136\u9009\u62e9\u7684\u4f5c\u7528\u548c\u5206\u5e03\u4ee5\u53ca\u548cpandemics\/epidemics \u4e4b\u95f4\u7684\u76f8\u4e92\u5173\u7cfb\uff0chost-parasite evolution\u7b49\u7b49\u3002<\/p>\n

\u6d3b\u52a8\u5bb6\u662f\u7b2c\u4e09\u65b9\u5609\u5bbe\u9080\u7ea6\u5e73\u53f0\u3002\u53ef\u6839\u636e\u6f14\u8bb2\u8bae\u9898\u3001\u4f1a\u8bae\u65e5\u671f\u3001\u6d3b\u52a8\u9884\u7b97\u7b49\u8981\u6c42\uff0c\u4e3a\u60a8\u63d0\u4f9b\u8be5\u9886\u57df\u5185\u4e13\u4e1a\u5609\u5bbe\u6f14\u8bb2\u9080\u7ea6\u670d\u52a1\uff0c\u4e13\u5bb6\u5b66\u8005\u5609\u5bbe\u8fdc\u7a0b\u89c6\u9891\u5206\u4eab\u53d1\u8a00\uff0c\u795d\u798f\u81f4\u8f9e\u89c6\u9891\u62cd\u6444\uff0c\u7f51\u7ea2\u660e\u661f\u827a\u4ebaVCR\u6d3b\u52a8\u5f55\u5236\uff0c\u4ee3\u8a00\u9080\u7ea6\uff0c\u4f01\u4e1a\u5bb6\u56fd\u9645\u987e\u95ee\u54a8\u8be2\u670d\u52a1\u3002\u60a8\u53ef\u51c6\u5907\u597d\u6d3b\u52a8\u4fe1\u606f\u540e\uff0c\u8054\u7cfb\u7535\u8bdd\uff1a18911802888\uff08\u738b\u8001\u5e08\uff09\uff08\u5de5\u4f5c\u65e59\u65f6\u81f318\u65f6\uff0c\u4ec5\u9080\u7ea6\u5609\u5bbe\u51fa\u5e2d\u6d3b\u52a8\uff0c\u5176\u4ed6\u9700\u6c42\u52ff\u6270\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\u65b0\u52a0\u5761\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\uff0c\u9ad8\u7ea7\u7814\u7a76\u5458\uff0c\u8fdb\u5316\u57fa\u56e0\u7ec4\u5b66\u65b9\u5411\u3002\u53d1\u8868\u6587\u7ae015\u7bc7\u3002 \u5dcd\u5dcd\u535a\u58eb\u81f4\u529b\u4e8e\u7814\u7a76\u901a\u8fc7\u5168\u57fa\u56e0\u7ec4\u6570\u636e\u8fdb\u884c\u79cd\u7fa4...<\/p>\n

Read More “\u7fdf\u5dcd\u5dcd\u7b80\u5386_\u65b0\u52a0\u5761\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\u9ad8\u7ea7\u7814\u7a76\u5458\u7fdf\u5dcd\u5dcd\u53d7\u9080\u53c2\u4f1a\u6f14\u8bb2_\u6d3b\u52a8\u5bb6”<\/span> »<\/a><\/p>\n","protected":false},"author":23,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[10680],"tags":[],"class_list":["post-194489","post","type-post","status-publish","format-standard","hentry","category-10680"],"_links":{"self":[{"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/posts\/194489"}],"collection":[{"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/comments?post=194489"}],"version-history":[{"count":0,"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/posts\/194489\/revisions"}],"wp:attachment":[{"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/media?parent=194489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/categories?post=194489"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/m.catawbaoil.com\/wp-json\/wp\/v2\/tags?post=194489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}